Perfudal.
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Perfudal Indications
Perfudal contains the active ingredient felodipine, which is a type of drug called a calcium channel blocker. This type of drug acts on the heart and blood vessels.
Perfudal is indicated for the treatment of high blood pressure. It is effective alone or in combination with other high blood pressure medications. A type of medication called a calcium channel blocker, Perfudal eases the workload of the heart by slowing down its muscle contractions and the passage of nerve impulses through it. This improves blood flow through the heart and throughout the body, reduces blood pressure, and helps prevent angina pain (chest pain, often accompanied by a feeling of choking, usually caused by lack of oxygen in the heart due to clogged arteries).
Perfudal works by slowing the movement of calcium through the muscle cells that are found in the walls of blood vessels. It acts specifically on the muscle cells in the walls of small arteries. Felodipine slows calcium movement by blocking 'calcium channels' in these muscle cells. Calcium is needed by muscle cells in order for them to contract, so felodipine causes the muscle in the walls of the small arteries to relax. This widens the small arteries in the body, an effect that has two uses.
The relaxing and widening of the small arteries in the body decreases the resistance that the heart has to push against in order to pump the blood around the body. This reduces blood pressure. Felodipine can therefore be indicated to treat high blood pressure.
The widening effect on the small arteries improves the blood and therefore oxygen supply to the heart. This feature means felodipine can be indicated to treat angina. The chest pain of angina is caused by insufficient oxygen supply to the heart. As felodipine improves this oxygen supply, and reduces the effort the heart has to make to pump blood, it can be indicated to prevent angina attacks.
Perfudal is indicated for the treatment of:
- High blood pressure;
- Angina pectoris;
Perfudal Side Effects
Perfudal side effects that you should report to your health care professional or doctor as soon as possible:
- Ankle swelling;
- Awareness of your heart beat;
- Dizziness;
- Enlargement of the gums;
- Fatigue;
- Flushing;
- Headache;
- Impotence;
- Rash or itching;
- Worsening of anginal chest pains;
- Flushing;
- Headache;
- Swelling of the legs and feet;
Perfudal Dosage
CHILDREN
The safety and effectiveness of Perfudal in children have not been established.
ADULTS
The usual starting dose is 5 mg once a day; your doctor will adjust the dose at intervals of not less than 2 weeks.
Your doctor will adjust the dosage according to your response to Perfudal.
The usual dosage range is 2.5 to 10 mg once daily.
OLDER ADULTS
People with liver problems usually require lower doses of Perfudal and are carefully monitored while the dose is adjusted.
If you are over 65 years of age, your doctor will start treatment with a dosage of 2.5 mg once a day and will monitor your blood pressure closely during dosage adjustment.
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